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  #1  
Old Sun Oct 30, 2016, 10:29 PM
lisa3112 lisa3112 is offline
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Chlorsig eye drops

Hi, just wondering if you have been warned against using chlorsig eye drops 0.5%? I have a gunky right eye, went and got drops from pharmacy.. got home and read "do not use if you have bone marrow supression".
Very annoying as I've used this post transplant a couple of times!
Thanks, Lisa
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Now 30yr old. Diagnosed AML dec 2015 (Most likely MDS prior). Trisomy 6. Runx1 mutation also. Had induction and consolidation chemo. Marrow failure ++ so SCT on 21st of March with MUD. Married with a 1yr old!
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  #2  
Old Mon Oct 31, 2016, 09:13 AM
Neil Cuadra Neil Cuadra is offline
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Lisa,

The active ingredient is chloramphenicol, which is known to cause aplastic anemia, lower blood counts (red cells, white cells, and platelets), and has been reported to cause PNH as well.

I believe it was taken off the market in the U.S. for that reason, but continues to be available in Australia.

You'll need to find another type of eye drops. I'm glad you spotted that warning.
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Old Tue Nov 1, 2016, 02:55 AM
Cheryl C Cheryl C is offline
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Thank you for the warning. I used Chlorsig recently for an eye infection and have done so several times since being diagnosed with MDS.
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Dx MDS RAEB 10% blasts + hypogammaglobulinemia, Sep 2011. Jan 2012 BMB - blasts down to 2% w/out treatment so BMT cancelled. Re-diagnosis RCMD. On watch and wait since Feb 2012. IVIg 5-weekly. BMB Feb 2014 - no blast transformation. 2018 still stable.
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  #4  
Old Tue Nov 1, 2016, 04:26 AM
lisa3112 lisa3112 is offline
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Hi Neil, thanks for the reply! I actually emailed my transplant nurse. He said the consultant was ok with me continuing it... but I think I'll give it a miss!
Cheryl its amazing how many drugs affect your bone marrow isn't it :/
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Now 30yr old. Diagnosed AML dec 2015 (Most likely MDS prior). Trisomy 6. Runx1 mutation also. Had induction and consolidation chemo. Marrow failure ++ so SCT on 21st of March with MUD. Married with a 1yr old!
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  #5  
Old Tue Nov 1, 2016, 02:05 PM
Neil Cuadra Neil Cuadra is offline
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Maybe the consultant is thinking about how important it is to protect your eyes. But I hope they can recommend another brand of eye drops for you to use.
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  #6  
Old Tue Nov 1, 2016, 05:17 PM
Cheryl C Cheryl C is offline
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I'm usually very careful to read all the info about drugs, but because I've used Chlorsig over so many years, neglected to do this recently. A lesson learned!
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Dx MDS RAEB 10% blasts + hypogammaglobulinemia, Sep 2011. Jan 2012 BMB - blasts down to 2% w/out treatment so BMT cancelled. Re-diagnosis RCMD. On watch and wait since Feb 2012. IVIg 5-weekly. BMB Feb 2014 - no blast transformation. 2018 still stable.
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