Home         Forums  

Go Back   Marrowforums > Practical Issues > Questions and Answers
Register FAQ Search Today's Posts Mark Forums Read

Questions and Answers Not sure where to post a question? Post it here.

Reply
 
Thread Tools Search this Thread
  #1  
Old Sun Apr 4, 2010, 10:57 AM
lotusbud lotusbud is offline
Member
 
Join Date: Apr 2010
Posts: 53
Immunophenotyping

Anybody has experience or direction where to find information on immunophenotyping - CD54, CD34, CD117, etc. in bonemarrow biopsy?
Are certain types indicative of certain disorders, like I know by combining these one can know the maturation stage of a cell?
Thank you...
Reply With Quote
  #2  
Old Sun Apr 4, 2010, 11:50 PM
Ruth Cuadra Ruth Cuadra is offline
Administrator
 
Join Date: Jul 2006
Location: Los Angeles, California
Posts: 611
Hi, lotusbud.

There are more than 250 types of CD (cluster of differentiation) molecules on the surfaces of cells in our bodies. Because they are useful for classifying white blood cells, they are used in diagnosing lymphoma, leukemia, and MDS, each which involve WBCs.

You can find general information and links to specific information about certain common markers at
http://en.wikipedia.org/wiki/Cluster_of_differentiation

Technical details about specific markers can also be found at http://www.pathologyoutlines.com/cdmarkers.html

Hope this helps,
Ruth
__________________
Diagnosed AA 10/96, MDS/RA 6/98, MUD/BMT 10/6/98
Reply With Quote
  #3  
Old Mon Apr 5, 2010, 02:10 PM
lotusbud lotusbud is offline
Member
 
Join Date: Apr 2010
Posts: 53
Immunophenotypes

Thank you Ruth,
I checked both of these sites and wracked my brain. It is quite fascinating though, the same thing a little too much is no good, a too little too. Apparently flow cytometry and immunophenotyping is fairly new but apparently a powerful tool to find out what is going on in the bone marrow. However it seems not so straitforward... Then the question would be what are the normal values in a bonemarrow, when there is an abnormality.
Reply With Quote
Reply


Thread Tools Search this Thread
Search this Thread:

Advanced Search

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

vB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Forum Jump

Similar Threads
Thread Thread Starter Forum Replies Last Post
Where Do I find normal values of bone marrow aspirate and immunophenotyping ? robsp Questions and Answers 2 Tue Nov 25, 2014 08:23 PM
Immunophenotyping by flow cytometry lotusbud Bone Marrow Failure 4 Sat Jan 14, 2012 12:40 PM


All times are GMT -4. The time now is 12:59 AM.


Powered by vBulletin® Version 3.6.7
Copyright ©2000 - 2019, Jelsoft Enterprises Ltd.
Forum sites may contain non-authoritative and unverified information.
Medical decisions should be made in consultation with qualified medical professionals.
Site contents exclusive of member posts Copyright 2006-2019 Marrowforums.org