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AA Aplastic anemia

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Old Thu Feb 21, 2013, 07:40 AM
Janire Janire is offline
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Join Date: Apr 2011
Posts: 19
AA new treatment??

Anyone knows anything about this?? Could it be a light in the dark?

http://www.globes.co.il/serveen/glob...24194&fid=1725
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Janire, age 31, diagnosed AA september 2007; treated with ATG november 2007, no response; 2xATG april 2008, total remission..... RELAPSE and 3xATG in april 2011....now waiting for a response... not always easy. Http://anemiaaplasica.blogspot.com
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Old Thu Feb 21, 2013, 08:35 AM
Marlene Marlene is offline
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Join Date: Oct 2006
Location: Springfield, VA
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It has promise for improving outcomes for cord blood transplants.

http://www.pluristem.com/index.php?o...=116&Itemid=62

Here's their latest press releases regarding AA.

http://www.pluristem.com/index.php?s...ion=com_search
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Marlene, wife to John DX w/SAA April 2002, Stable partial remission; Treated with High Dose Cytoxan, Johns Hopkins, June 2002. Final phlebotomy 11/2016. As of January 2017, FE is 233, HGB 11.7, WBC 5.1/ANC 4.0, Plts 146K.
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Old Mon Feb 25, 2013, 01:59 AM
dfantle dfantle is offline
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Location: bellevue, wa
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Hi, the NIH has a cordblood transplant study underway for AA patients which might be worth looking into.

Regarding the expanded cord blood study you're referring to, I know of a team in Seattle who has been working hard on this, so perhaps there are other research centers doing this as well. I believe the reasoning is to decrease the time to engraftment for cord blood transplant patientss.

When cord blood is used for transplants, it takes a longer time for engraftment, because cord blood cells are less mature than stem cells. The hope is that by using expanded cord blood cells, the patient will engraft sooner putting patients at lower risk for infection and possibly shorter hospital stays and likely other things...
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Dena
Age 54; DX Heavy Chain (AH) Amyloidosis 6/10; AutoSCT 3/11; Amyloidosis remission 6/11; DX SAA 7/11; Horse ATG 3/12; Mini MUD SCT 1/13; Recovered from SAA 5/13 & feeling great
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