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Old Thu Mar 2, 2017, 08:00 PM
julieme julieme is offline
Join Date: Dec 2016
Location: Monona
Posts: 10
Still low platlets

Hi, My husband had his 100 day post transplant biopsy.

No evidence of AML
BM doing well all donor.
Neutraphils, W & R cells low normal
Platelets 12

Dr does not seem worried thinks he has antibody from lots of platelet transfusions and says take it easy & wait...

Any ideas?
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Old Sat Mar 4, 2017, 04:19 PM
Data Data is offline
Join Date: Sep 2014
Location: Florida
Posts: 223
Similar Situtation

At Day 100, my counts were similar to your husband's except my platelets were low normal. Around Day 188 my platelets took a nose dive down in the single digits. I got platelet transfusions every other or ever third day for about two months. My doctor increased my prednisone. The platelet count climbed back (to 100) up for a while and then took another nose dive to which they have not recovered. He now has me on Rituxan. I have gotten two infusions and have two more to go (spaced out weekly). At that point he says he will evaluate whether the Rituxan is helping or not. So far, it hasn't - I am still getting platelet transfusions every couple days.

I am curious as to what your doctor thinks and what he does. Best of luck to your husband and you.

Prostate Cancer: Treated in early 2013 with HDR Brachytherapy. MDS-RCMD: Oct 2014. Biopsies: 46,XY,t(7;18)[2]: 46,XY,del(7)( q22)[3]: 45,XY,-7[6]: 45,XY,-7[10]: 45,XY,-7[13]. HSCT in April 2016.
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Old Sat Mar 4, 2017, 11:27 PM
julieme julieme is offline
Join Date: Dec 2016
Location: Monona
Posts: 10
Hi Data,
No platelet transfusions so far. The new marrow is making enough platelets and and they are normal healthy ones. Unfortunately the doctor feels that all my husbands previous transfusions of platelets left him with antibodies that will die out, He is on prednison for a skin rash.

he is at UW Madison Carbone cancer center. Work will cover a cansult at cleveland clinic if we want but the doctor seems to think waiting is the right thing to do at this point.
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Old Mon Mar 6, 2017, 11:58 AM
GoodDay5150 GoodDay5150 is offline
Join Date: Sep 2014
Location: Centennial, CO
Posts: 92
Hi Julieme. A very long time ago, late 1990's I had a blood test done and the dr commented on my platelets being low normal. Fast forward to when I was diagnosed w/ PNH in 2011 and now 5 years after my transplant and my platelets are still low normal. My transplant doc has said more than once that low normal platelets are not that uncommon. Other than red cells twice when was in the hospital getting a transplant I have never had any other transfusions or meds to stimulate call growth. I would also keep in mind that everyone reacts differently to the whole pre and post transplant regimen. The opinion of the transplant doc is probably correct. It sounds as if your husband is mostly doing well.

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