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#1
Sun Oct 30, 2016, 10:29 PM
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Chlorsig eye drops
Hi, just wondering if you have been warned against using chlorsig eye drops 0.5%? I have a gunky right eye, went and got drops from pharmacy.. got home and read "do not use if you have bone marrow supression".
Very annoying as I've used this post transplant a couple of times! Thanks, Lisa
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Now 30yr old. Diagnosed AML dec 2015 (Most likely MDS prior). Trisomy 6. Runx1 mutation also. Had induction and consolidation chemo. Marrow failure ++ so SCT on 21st of March with MUD. Married with a 1yr old! 
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#2
Mon Oct 31, 2016, 09:13 AM
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Lisa,
The active ingredient is chloramphenicol, which is known to cause aplastic anemia, lower blood counts (red cells, white cells, and platelets), and has been reported to cause PNH as well. I believe it was taken off the market in the U.S. for that reason, but continues to be available in Australia. You'll need to find another type of eye drops. I'm glad you spotted that warning.
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#3
Tue Nov 1, 2016, 02:55 AM
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Thank you for the warning. I used Chlorsig recently for an eye infection and have done so several times since being diagnosed with MDS.
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Dx MDS RAEB 10% blasts + hypogammaglobulinemia, Sep 2011. Jan 2012 BMB - blasts down to 2% w/out treatment so BMT cancelled. Re-diagnosis RCMD. Watch and wait from Feb 2012. IVIg 5-weekly. New diagnosis Oct 2019 AML 23% blasts in marrow, 10% blasts in peripheral blood.
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#4
Tue Nov 1, 2016, 04:26 AM
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Hi Neil, thanks for the reply! I actually emailed my transplant nurse. He said the consultant was ok with me continuing it... but I think I'll give it a miss!
Cheryl its amazing how many drugs affect your bone marrow isn't it :/
__________________
Now 30yr old. Diagnosed AML dec 2015 (Most likely MDS prior). Trisomy 6. Runx1 mutation also. Had induction and consolidation chemo. Marrow failure ++ so SCT on 21st of March with MUD. Married with a 1yr old!
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#5
Tue Nov 1, 2016, 02:05 PM
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Maybe the consultant is thinking about how important it is to protect your eyes. But I hope they can recommend another brand of eye drops for you to use.
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#6
Tue Nov 1, 2016, 05:17 PM
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I'm usually very careful to read all the info about drugs, but because I've used Chlorsig over so many years, neglected to do this recently. A lesson learned!
__________________
Dx MDS RAEB 10% blasts + hypogammaglobulinemia, Sep 2011. Jan 2012 BMB - blasts down to 2% w/out treatment so BMT cancelled. Re-diagnosis RCMD. Watch and wait from Feb 2012. IVIg 5-weekly. New diagnosis Oct 2019 AML 23% blasts in marrow, 10% blasts in peripheral blood.
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