Home         Forums  

Go Back   Marrowforums > Practical Issues > Questions and Answers
Register FAQ Search Today's Posts Mark Forums Read

Questions and Answers Not sure where to post a question? Post it here.

Reply
 
Thread Tools Search this Thread
  #1  
Old Sun Jan 22, 2017, 10:44 AM
Lennyr Lennyr is offline
Member
 
Join Date: Nov 2016
Location: Somerset new jersey
Posts: 7
Bone marrow biopsies very painful

My 75 year old husband is being considered for a trial on rigosertib. One of the problems is the Bone marrow biopsies are very painful for him and to be on the trial he must get them frequently. Can anyone offer information that would make these tests more tolerable. He may opt out of the trial bc of this. Thank you . Lenore his wife
Reply With Quote
  #2  
Old Sun Jan 22, 2017, 12:02 PM
bailie bailie is offline
Member
 
Join Date: Dec 2013
Location: McMinnville,OR
Posts: 825
Welcome to the forum! Bone marrow biopsies, like these diseases, seem differently for many people. I have had 19 BMBs and have had no problem except the ten seconds when they draw the marrow. That gets most everyone's attention. I have had no after effects ever. The important thing I think is to match a person's pain tolerance with the pre-medication. For me Lidocaine was used for local anesthesia followed by Fentanyl 50 mcg IV. Some people need to be "put out" completely. I wish both of you the best.
__________________
age 70, dx RAEB-2 on 11-26-2013 w/11% blasts. 8 cycles Vidaza 3w/Revlimid. SCT 8/15/2014, relapsed@Day+210 (AML). Now(SCT-Day+1005). Prepping w/ 10 days Dacogen for DLI on 6/9/2017.

Last edited by bailie : Sun Jan 22, 2017 at 07:48 PM.
Reply With Quote
  #3  
Old Sun Jan 22, 2017, 03:12 PM
Lennyr Lennyr is offline
Member
 
Join Date: Nov 2016
Location: Somerset new jersey
Posts: 7
Thank you for your response Bailie. What is fentanyl. Is that through an Iv?
Reply With Quote
  #4  
Old Sun Jan 22, 2017, 03:21 PM
bailie bailie is offline
Member
 
Join Date: Dec 2013
Location: McMinnville,OR
Posts: 825
From Wikipedia, "Fentanyl (also known as fentanil) is a potent, synthetic opioid pain medication with a rapid onset and short duration of action. It is a potent agonist at the μ-opioid receptors. Fentanyl is 50 to 100 times more potent than morphine.

I can't tell the effect from the fentanyl but it must work fine for me. Yes, it is administered by IV.
__________________
age 70, dx RAEB-2 on 11-26-2013 w/11% blasts. 8 cycles Vidaza 3w/Revlimid. SCT 8/15/2014, relapsed@Day+210 (AML). Now(SCT-Day+1005). Prepping w/ 10 days Dacogen for DLI on 6/9/2017.
Reply With Quote
  #5  
Old Sun Jan 22, 2017, 03:26 PM
Neil Cuadra Neil Cuadra is offline
Owner
 
Join Date: Jul 2006
Location: Los Angeles, California
Posts: 2,353
Lenny,

My wife had quite a few bone marrow biopsies. For her, local/topical pain relief wasn't enough, so for bone marrow biopsies the hospital started giving her the surgical anesthetic propofol (brand name Deprival), by IV. It worked perfectly to prevent the pain, and recovery was quick and easy. As an added benefit, her hematologist said that they got a better bone marrow sample because her body was relaxed instead of tensed due to the pain. Not all treatment centers take pain issues seriously enough to do this, so you have to speak up about it. Start by asking what pain relief options they have available, and let them know if the answer isn't satisfactory. That's what we did.
Reply With Quote
  #6  
Old Sun Jan 22, 2017, 07:34 PM
rar rar is offline
Member
 
Join Date: Mar 2014
Location: colorado
Posts: 187
I had about a dozen BMB. Most of them was no worse than a mosquito bite. On one the local anesthetic didn't work and hurt pretty bad. Find a NP who knows how to give a shot and stay with them.

Ray
Reply With Quote
  #7  
Old Tue Jan 24, 2017, 03:45 AM
lisa3112 lisa3112 is offline
Member
 
Join Date: Jun 2016
Location: Melbourne
Posts: 67
I LOVE fentanyl and midazolam! They both don't last long in your system and you feel totally relaxed. Maybe ring and ask them. Im sure they will help you in any way to get ppl in study. Good luck.
__________________
Now 30yr old. Diagnosed AML dec 2015 (Most likely MDS prior). Trisomy 6. Runx1 mutation also. Had induction and consolidation chemo. Marrow failure ++ so SCT on 21st of March with MUD. Married with a 1yr old!
Reply With Quote
Reply


Thread Tools Search this Thread
Search this Thread:

Advanced Search

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

vB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Forum Jump

Similar Threads
Thread Thread Starter Forum Replies Last Post
Cryo-Preserved Bone Marrow Bank? Anthony Transplants 6 Sat Nov 15, 2014 01:02 PM
Confused with Bone marrow report teo MDS 168 Mon May 5, 2014 10:20 AM
Hypoplastic Bone Marrow No Problem? Shazza Tell Your Story 3 Thu Feb 20, 2014 05:20 AM
Recommended frequency of follow up bone marrow biopsies? Paul AA 16 Mon Mar 12, 2012 01:47 PM


All times are GMT -4. The time now is 05:18 AM.


Powered by vBulletin® Version 3.6.7
Copyright ©2000 - 2018, Jelsoft Enterprises Ltd.
Forum sites may contain non-authoritative and unverified information.
Medical decisions should be made in consultation with qualified medical professionals.
Site contents exclusive of member posts Copyright 2006-2016 Marrowforums.org