| Home Forums |
|
|||||||
| Transplants Bone marrow and stem cell transplantation |
 |
|
|
Thread Tools | Search this Thread |
|
#1
Fri Jul 15, 2011, 07:51 AM
|
|||
|
|||
|
St Jude's BMT survival rate
St. Jude's improvement of survival rate for high risk leukemia patients.
http://www.sciencedaily.com/releases...0714120846.htm
__________________
Marlene, wife to John DX w/SAA April 2002, Stable partial remission; Treated with High Dose Cytoxan, Johns Hopkins, June 2002. Final phlebotomy 11/2016. As of July 2021 HGB 12.0, WBC 4.70/ANC 3.85, Plts 110K. 
|
|
#2
Fri Jul 15, 2011, 09:33 AM
|
|||
|
|||
|
St Jude's BMT rates
Marlene,
Thanks for the article. I notice all the articles talk about improved BMT for leukemia but would it also apply to BMT for AA. Is there a difference in success for different types of disease? Thanks
__________________
Jody, mother or Trevor 23. Diagnosed VSAA 3/11 , ATG cyclosporin 3/11 response 6/11, Relapse 1/13, Round 2 ATG 1/13
|
|
#3
Fri Jul 15, 2011, 10:16 AM
|
|||
|
|||
|
Hi Jody,
I don't really know the answer to that but it would make sense that it would work just as well in AA where ATG has failed and there is no matching donor for child. I think that's why it is so important to find out what you can from the different BMT centers on what protocols they use so you can make informed choice on where to go. You really want the least toxic, most effect protocol with good outcomes. Especially with GVHD. It saddens me to read about those who have successful BMTs but end up major GVHD.
__________________
Marlene, wife to John DX w/SAA April 2002, Stable partial remission; Treated with High Dose Cytoxan, Johns Hopkins, June 2002. Final phlebotomy 11/2016. As of July 2021 HGB 12.0, WBC 4.70/ANC 3.85, Plts 110K.
|
|
#4
Fri Jul 15, 2011, 01:57 PM
|
|||
|
|||
|
Hi All!
Even though I'm and MDSer, I watched this AAMDS presentation (from March) on SCT for AA the other day and was very interested to learn about the differences in transplant for the two diseases. The presenter, Dr. Noel, said one key difference is that, in MDS, you typically want a little GVHD, to help kill off the cancerous stem cells in the marrow. In AA, you don't have those bad stem cells to worry about, so the aim is to, if possible, completely eliminate GVHD. So there's a bit more of a balancing act in the MDS cases. The whole lecture was really very fine; I recommend it. Take Care! Greg
__________________
Greg, 59, dx MDS RCMD Int-1 03/10, 8+ & Dup1(q21q31). NIH Campath 11/2010. Non-responder. Tiny telomeres. TERT mutation. Danazol at NIH 12/11. TX independent 7/12. Pancreatitis 4/15. 15% blasts 4/16. DX RAEB-2. Beginning Vidaza to prep for MUD STC. Check out my blog at www.greghankins.com
|
|
#5
Fri Jul 15, 2011, 02:37 PM
|
|||
|
|||
|
Yeah, that makes sense. Same would hold true with AML/ALL.
__________________
Marlene, wife to John DX w/SAA April 2002, Stable partial remission; Treated with High Dose Cytoxan, Johns Hopkins, June 2002. Final phlebotomy 11/2016. As of July 2021 HGB 12.0, WBC 4.70/ANC 3.85, Plts 110K.
|
|
| Thread Tools | Search this Thread |
|
|
Similar Threads
|
||||
| Thread | Thread Starter | Forum | Replies | Last Post |
| Questions to ASK at BMT Consult | NLJabbari | Transplants | 4 | Tue Oct 29, 2013 09:51 PM |
| Cigarette smoking shortens the survival of patients with low-risk myelodysplastic syn | akita | MDS | 1 | Wed Feb 9, 2011 11:25 AM |
| IPSS Survival Rates | gbrilla | Questions and Answers | 4 | Sat Dec 6, 2008 02:57 PM |
| Can anyone tell me what the Survival Rate is for MDS | alicat4790 | Transplants | 1 | Thu Sep 25, 2008 12:39 AM |
