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Tue Jan 12, 2016, 11:17 PM
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Help with bmb cytogenics
47,XY,+8[16]/50,idem,+8,+19,+21[4]
INTERPRETATION: Chromosome analysis reveals an abnormal male karyotype with two related clones. The stemline clone (16/20 cells) shows trisomy 8. The sideline clone (4/20 cells) shows tetrasomy 8 and trisomies 19 and 21. Trisomy 8 was observed in the previous studies. The presence of additional aberrations is suggestive of clonal evolution. This is different from bmb in September that showed +8 in all cells Any thoughts? 
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