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AA Aplastic anemia

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  #1  
Old Fri Aug 16, 2013, 05:33 AM
Lucky Lucky is offline
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Hepatitis A causing SAA?

Hi all,

Is there a chance of Hepatitis A to cause SAA? I know somebody who had Hepatitis A and after a year, he developed SAA. Has anybody experienced similar case, or do you know somebody with similar case?


Thanks a lot
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Old Fri Aug 16, 2013, 12:15 PM
Neil Cuadra Neil Cuadra is offline
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Yes, it could be hepatitis-associated aplastic anemia. Suspected causes of acquired aplastic anemia include ionizing radiation, chemotherapy, benzene-based compounds, environmental toxins, and viruses like hepatitis.

Here are some articles than mention the connection:
A Marked Decrease in CD4-Positive Lymphocytes at the Onset of Hepatitis in a Patient With Hepatitis-Associated Aplastic Anemia.

Etiology and survival of aplastic anemia: a study based on clinical investigation.

Billy Kiesel, Texas Musician Overcomes Aplastic Anemia Acquired Through Bout with Hepatitis
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Old Sat Aug 17, 2013, 01:32 AM
Lucky Lucky is offline
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Quote:
Originally Posted by Neil Cuadra View Post
Yes, it could be hepatitis-associated aplastic anemia. Suspected causes of acquired aplastic anemia include ionizing radiation, chemotherapy, benzene-based compounds, environmental toxins, and viruses like hepatitis.

Here are some articles than mention the connection:
A Marked Decrease in CD4-Positive Lymphocytes at the Onset of Hepatitis in a Patient With Hepatitis-Associated Aplastic Anemia.

Etiology and survival of aplastic anemia: a study based on clinical investigation.

Billy Kiesel, Texas Musician Overcomes Aplastic Anemia Acquired Through Bout with Hepatitis
Thank You! So, as I understand, there is no particular treatment for AA when it is caused by hepatitis viruses? I went through the links you shared and patients whose AA was coming from hepatitis got ATG/Cyclo treatment? which is a general treatment for AA...
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Old Sat Aug 17, 2013, 09:35 AM
Neil Cuadra Neil Cuadra is offline
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Yes, it's generally true that the specific cause of aplastic anemia, in the cases where it's known at all, doesn't affect the treatment choice.
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