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#1
Sun May 25, 2014, 05:49 PM
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Telintra? MDS and neutropenia
Http://www.telik.com/pipe_telintra.html
This is all I can paste from my phone at the moment. It looks promising for people with neutropenia. Looks like it inhibits tumor growth something that is of risk in long term treatment of neupogen. I don't know how far they are with this. I have seen a patient suffering from severe neutropenia and not responding to neupogen I believe. Once she was placed on this med her neutrophils increased to normal and good thing is these are tablets.
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Diagnosed PNH 2014/ Autoimmune AA 2006 treated with prednisone/ Hemoglobin 10.1; ANC .55; Platelets 150K 
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#2
Sun May 25, 2014, 09:06 PM
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Is Telintra another form of chemotherapy like Vidaza and Revlimid?
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Dx MDS RAEB 10% blasts + hypogammaglobulinemia, Sep 2011. Jan 2012 BMB - blasts down to 2% w/out treatment so BMT cancelled. Re-diagnosis RCMD. Watch and wait from Feb 2012. IVIg 5-weekly. New diagnosis Oct 2019 AML 23% blasts in marrow, 10% blasts in peripheral blood.
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#3
Mon May 26, 2014, 12:20 AM
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There have been some studies with Telintra. Here is one.
http://www.mdsbeacon.com/tag/telintra/ Telintra response has some predictable markers per the study noted above. Hope this helps.
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MDS RCMD w/grade 2-3 fibrosis. Allo-MUD Feb 26, 2014. Relapsed August 2014. Free and clear of MDS since November 2014 after treatment with Vidaza and Rituxan. Experiencing autoimmune attack on CNS thought to be GVHD, some gut, skin and ocular cGVHD. Neuropathy over 80% of body.
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