Ocular GVHD

[Marlene]

Here's an article on treating ocular graft vs host disease.

https://www.sciencedaily.com/release...0413180343.htm

[Neil Cuadra]

Thanks for posting this, Marlene.

It's good news that's there's an better alternative for post-transplant patients who have had to use steroids to avoid dry eyes or eye damage,

[Marlene]

I was curious to see if they did a study comparing Restasis to tacrolimus to see how they compared. I did a brief check but only found a study or two comparing them for the treatment of dry eyes and not ocular GVHD. It appears that when people cannot use Restasis anymore due to side effects, tacrolimus works for them and maybe even better.

It would be good to know if they are using Restates for GVHD now and if they compared Restasis to tacrolimus specifically for GVHD.

[rar]

I am using Restasis, FML, Muro ointment, and preservative free drops. My oncologist is not an eye doctor and my eye doctor is not an GVHD expert. I can't find a doctor who is well versed in both fields. The eyes still do what they want, sometimes pretty good and then bad.

Ray

[Marlene]

Here's one article looking at Restasis and tacrolimis. Seem both are pretty equally effective and tacrolimis is a good option if Restasis become problematic.

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787325/