Home         Forums  

Go Back   Marrowforums > Bone Marrow Failure Diseases > MDS
Register FAQ Search Today's Posts Mark Forums Read

MDS Myelodysplastic syndromes

Reply
 
Thread Tools Search this Thread
  #1  
Old Wed Sep 27, 2017, 06:58 PM
Bossywife Bossywife is offline
Member
 
Join Date: Apr 2015
Location: Canada
Posts: 103
Tired from low platelets

My husband's numbers are decent, his platelets are 50-90 usually and his WBC is a bit low. He is very active, plays hockey, lots of walking at work... But lately he has been very tired. Could it be the platelets? His blood is checked monthly, so we would know if it was worsening.
__________________
Husband (61) dx RAEB1 Apr 2015 after long term bad CBCs (first discovered Apr 2008 after an unknown infection had him hospitalized), currently on watch & wait with monthly bloodwork. Myeloid Gene Panel testing done Aug 2017, showed nothing worrisome. CEBPA mutation
Reply With Quote
  #2  
Old Wed Sep 27, 2017, 08:10 PM
Sally C Sally C is online now
Member
 
Join Date: Dec 2010
Location: Chesterfield, Va.
Posts: 467
Hi Bossywife,
My husband's oncologist told us that it is actually the whites being low that made people feel bad. I don't think it's due to the platelets unless he has a bleed somewhere.
Best wishes,
Sally
Reply With Quote
  #3  
Old Thu Sep 28, 2017, 12:56 AM
DanL DanL is offline
Member
 
Join Date: Dec 2010
Location: Denver, CO
Posts: 590
Low platelets were the primary symptom of my MDS for the first 3+ years and I did not experience fatigue as a result of being in the 20k-30k range during this time.

Aside from normal causes of fatigue, with MDS, as Sally C mentioned, it can be tied to low WBC or RBC.
__________________
MDS RCMD w/grade 2-3 fibrosis. Allo-MUD Feb 26, 2014. Relapsed August 2014. Free and clear of MDS since November 2014 after treatment with Vidaza and Rituxan. Experiencing autoimmune attack on CNS thought to be GVHD, some gut, skin and ocular cGVHD. Neuropathy over 80% of body.
Reply With Quote
  #4  
Old Thu Sep 28, 2017, 04:18 PM
Bossywife Bossywife is offline
Member
 
Join Date: Apr 2015
Location: Canada
Posts: 103
My husband's WBC is below normal, but not critically low. That can cause exhaustion?
__________________
Husband (61) dx RAEB1 Apr 2015 after long term bad CBCs (first discovered Apr 2008 after an unknown infection had him hospitalized), currently on watch & wait with monthly bloodwork. Myeloid Gene Panel testing done Aug 2017, showed nothing worrisome. CEBPA mutation
Reply With Quote
  #5  
Old Thu Sep 28, 2017, 08:03 PM
Callie Callie is offline
Member
 
Join Date: Jan 2014
Location: Fayetteville, NC
Posts: 25
My dad's reds/Hgb/HCT stayed pretty constant over the 3 1/2 years, so any fatigue wasn't associated with that. But, his platelets did fluctuate quite a bit and he did seem to feel much more tired when they dropped (the whites usually decreased at the same time, but the platelets were the most drastic)...
__________________
Daughter of Bailie (diagnosed RAEB-2 11/13; transplant 08/14; relapse with Ph+ AML 04/15; remission until 04/17; DLI 06/17; passed away 07/11/17 at Day+1059)...the best dad a daughter could have...
Reply With Quote
  #6  
Old Fri Sep 29, 2017, 06:46 AM
DaveAvl DaveAvl is offline
Member
 
Join Date: Aug 2017
Location: Asheville, NC
Posts: 8
Callie, thanks for that. I just passed it along to my husband who replied, "Well then I'm not imagining it..."
__________________
Dave age 70, husband of Alan age 67 who was a 25-year HIV survivor and was dx with MDS RAEB-1 5/24/17. Vidaza started 8/7/17. It was ineffective. Passed away 2/7/18.
Reply With Quote
  #7  
Old Mon Oct 2, 2017, 07:21 AM
Bossywife Bossywife is offline
Member
 
Join Date: Apr 2015
Location: Canada
Posts: 103
Would it hurt to give my husband a small iron supplement? If his HGB is mildly low?
__________________
Husband (61) dx RAEB1 Apr 2015 after long term bad CBCs (first discovered Apr 2008 after an unknown infection had him hospitalized), currently on watch & wait with monthly bloodwork. Myeloid Gene Panel testing done Aug 2017, showed nothing worrisome. CEBPA mutation
Reply With Quote
  #8  
Old Mon Oct 2, 2017, 05:55 PM
maggiemag maggiemag is offline
Member
 
Join Date: Sep 2012
Location: Cincinnati, OH - United States
Posts: 92
BW, you should check with your husband's physician first of all. We aren't doctors, or at least I'm not. That said, my oncologist, who tends to be overly thorough, checks my iron profile probably twice a year, bc I don't absorb oral iron. In your husband's work up, it is likely to have been checked. Additionally, iron stores are also checked, I believe, when a bone marrow biopsy is done. So his physician probably would have told you if he felt he would benefit from additional iron. You can have anemia from MDS and also have iron deficiency anemia. Also you said his HB is slightly low, but what is the number?
__________________
Margaret, age 68, dx MDS 5 q- 5/09- now RCMD; also MGUS. TP53 and TET2 mutations
Reply With Quote
  #9  
Old Wed Oct 4, 2017, 08:11 AM
lisa3112 lisa3112 is offline
Member
 
Join Date: Jun 2016
Location: Melbourne
Posts: 105
Has he had many blood transfusions in the past months? My iron levels are high because the iron you recieve in blood transfusions has no way to leave the body effectively. So maybe check levels before giving supps.
__________________
Now 30yr old. Diagnosed AML dec 2015 (Most likely MDS prior). Trisomy 6. Runx1 mutation also. Had induction and consolidation chemo. Marrow failure ++ so SCT on 21st of March with MUD. Married with a 1yr old!
Reply With Quote
  #10  
Old Fri Oct 6, 2017, 03:32 PM
Ugo Ugo is offline
Member
 
Join Date: May 2016
Location: Venice,FL
Posts: 6
tIRED FROM LOW PLATELETS

I started down this MDS road in 1902 when as a result of my annual pysical my CBC scores were below normal. Since that time my blood counts have remained in a band wavered on a regular basis. During those early years my main complaint was fatigue. When I told my hemo, the reply was to exercise. Honestly, I did not comply.. In turn I used B-12 lozenges which I really do not know if they really helped or that I thought that they did.

A little over three years ago I moved to Florida and in my development was a gym. I did begin to use the gym on a regullar basis and I do cardio for 30 minutes and resistance exercises for 15. I try to get there each day but it is usually 5 times a week. The exercise has helped with the fatigue.

This week my CBC was 2.20 WBC an 90 for platelets. At 80 years old I am thankful that my disease has not progressed beyond where it is. I can tell you though I am currently scheduled for an MRI for prostrate cancer. Who knows?
Reply With Quote
Reply


Thread Tools Search this Thread
Search this Thread:

Advanced Search

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

vB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Forum Jump

Similar Threads
Thread Thread Starter Forum Replies Last Post
Low platelets (since 04) and low mpv with bleeding DebJM78 Tell Your Story 22 Tue Aug 28, 2012 05:39 PM
cmml treatment low platelets mcgill54 Drugs and Drug Treatments 41 Wed Apr 20, 2011 02:28 PM
LOW platelets with reaction & Vidaza cheri MDS 6 Thu Nov 18, 2010 07:49 AM
Platelets low - waiting to try Vidaza knstone MDS 10 Thu Nov 20, 2008 08:54 AM
Eltrombopag for low platelets will perhaps be approved June 19 Birgitta-A Drugs and Drug Treatments 0 Sat May 31, 2008 03:08 PM


All times are GMT -4. The time now is 08:19 AM.


Powered by vBulletin® Version 3.6.7
Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.
Forum sites may contain non-authoritative and unverified information.
Medical decisions should be made in consultation with qualified medical professionals.
Site contents exclusive of member posts Copyright © 2006-2020 Marrowforums.org