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MDS Myelodysplastic syndromes

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Old Thu Jul 21, 2011, 03:43 PM
sophia68 sophia68 is offline
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Join Date: Jul 2008
Location: Florida
Posts: 23
Dad Recovered....

from his recent hospitalization after combined treatment of revlimid/dacogen caused his counts to drop severely (WBC 0.9, plt 22, hgb 5.4). We had quite a scare when the attending at the hospital who is familiar with daddy's case told us we should think about hospice. He developed an infection and was treated with antiobiotics, neupogen for the low WBC as well as plt and rbc tx. He resumed treatment with revlimid on 7/13/11 and the exjade.

He went to see his hematologist yesterday and his counts are as follows:

WBC 4.6
RBC 2.33
Hgb 6.8
Hct 20.2
Plt 195

Dad said his hematologist wants to try the 5-day treatment of dacogen again at an ever lower dosage, but considering his reaction and subsequent hospitalization from the last treatment, I'm not confident this is the way to go and afraid of what may occur the next time. The dr also wants him to get a BMB...not sure why?
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Dad (83) DX w/MDS-RARS on 6/10/06.Prev treated w/Vidaza & Thalomid w/o success. Treated w/Decitabine w/some imprv discont after no resp. TX dep as of Aug'10 (evry 2-3 wks). Curr tkg Revlimid since Feb'11. Exjade since Apr'11. Recd lwr dsg decitabine on 6/6/11 in comb w/rev.
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