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Transfusions and Iron Overload Blood and platelet transfusions, iron testing and treatments

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Old Sun Aug 20, 2017, 05:13 AM
Naive Naive is offline
Join Date: Jul 2016
Location: Gold Coast, Queensland, Australia
Posts: 77
Blood transfusion antibodies

Hello, I am hoping someone can answer a question for me. About 7 years ago I required numerous blood transfusions and I developed 8 different antibodies. I had about 7 years not needing transfusions (only the odd one here and there) but I'm now transfusion dependant again. I no longer have any antibodies. I'm confused that the antibodies can disappear but also relieved.

I was wondering if the loss of antibodies means that I have a immune system problem and that also means that I may not create (or have lost) antibodies in response to my vaccinations. Perhaps I'm not as protected against the flu etc that I thought I was.

My current neut count is 0.7 and my carer has the flu (she refused to get the flu injection) so I'm in close contact because I have to tend to her.

Thank you.

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Old Sun Aug 27, 2017, 02:38 PM
Hopeful Hopeful is offline
Join Date: Jan 2009
Location: California, USA
Posts: 723
Hi Carol,

I have wondered about this myself, as I have received many transfusions in the past. When I asked my doctor about this, they thought the antibodies would decrease over time, but they weren't entirely sure. Maybe that is why you must get a new flu shot every year, even if it is for the same strain.

Let us know what you hear on this topic!

Hope you are doing well.
53 yo female, dx 9/08, AA/hypo-MDS, subclinical PNH, ATG/CsA 12/08, partial response. small trisomy 6 clone, low-dose cyclosporine dependent
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