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MDS Myelodysplastic syndromes

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Old Wed Nov 21, 2012, 07:02 PM
Bambam Bambam is offline
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High Anti-Nuclear Antibodies

My last blood tests showed a high Anti-nuclear Antibody and my initial research suggests this could mean SLE. However, I believe it is also associated with other diseases. Does anybody have any experience with this?
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DX MDS RA Low Risk August 2012. DX Changed to MDS RAEB1. Progressed to AML July 2013. Participated in clinical chemo trial CPX351 and relapsed four months later in March 2014. Maintenance chemo -VIDAZA (AZA) stopped after 4 rounds. Awaiting full report from BMB.
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Old Thu Nov 22, 2012, 04:26 PM
ssdavi71416 ssdavi71416 is offline
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You might want to have a reumatologist's advice. They can take a while to see, so make an appointment ASAP if possible. I know that lupus and Reumatoid Athritis will prooduce a level of ANA. I think other autoimmune diseases will produce ANA.

Best Wishes

Scott
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Old Thu Nov 22, 2012, 04:32 PM
Bambam Bambam is offline
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Thanks, Scott. I'm not sure why neither the Hematologist or GP has contacted me about this elevated test result, but perhaps they are waiting for me to be symptomatic, or to see next month's results before doing anything. I do know I am starting to feel nausea/heartburn at the back of my mouth and on the back of the top of my tongue. Went to our local Natural Pharmacy, Finlandia, yesterday and am taking deglycerized licorice before meals and DigestMore HCI with meals to see if that helps. I would prefer to avoid the Nexium that was given to me a couple of weeks ago if possible.
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DX MDS RA Low Risk August 2012. DX Changed to MDS RAEB1. Progressed to AML July 2013. Participated in clinical chemo trial CPX351 and relapsed four months later in March 2014. Maintenance chemo -VIDAZA (AZA) stopped after 4 rounds. Awaiting full report from BMB.
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Old Fri Nov 23, 2012, 09:03 AM
Marlene Marlene is offline
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A positive ANA doesn't mean much on its own. Healthy people can have a positive ANA. Also, it's more common to see positive ANA's as we age.
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Marlene, wife to John DX w/SAA April 2002, Stable partial remission; Treated with High Dose Cytoxan, Johns Hopkins, June 2002. Final phlebotomy 11/2016. As of July 2021 HGB 12.0, WBC 4.70/ANC 3.85, Plts 110K.
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Old Sun Nov 25, 2012, 06:17 PM
Bambam Bambam is offline
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Thanks, Marlene. I was curious as it was a new result.
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DX MDS RA Low Risk August 2012. DX Changed to MDS RAEB1. Progressed to AML July 2013. Participated in clinical chemo trial CPX351 and relapsed four months later in March 2014. Maintenance chemo -VIDAZA (AZA) stopped after 4 rounds. Awaiting full report from BMB.
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