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#1
Mon Oct 15, 2012, 03:06 PM
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Good results for Sapacitabine (Estybon)
Hi All,
The researchers have presented info about the Phase II trial: http://www.equities.com/news/headlin...3314&cat=hcare Kind regards Birgitta-A 
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#2
Mon Oct 15, 2012, 03:31 PM
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The trial of sapacitabine was for int-2 or high risk MDS patients, age 60 and over, who had failed Vidaza or Dacogen. Sapacitabine appears to lengthen survival in these worst cases from the 4 to 6 month range to the 8 to 10 month range.
The trial studied three dosage schedules, finding that the best results were with 200 mg given twice daily for 7 days. Results weren't quite as good with 300 mg given once daily for 7 days or 100 mg given once daily for 5 days per week over 2 weeks.
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