Home         Forums  

Go Back   Marrowforums > Treatments > Transfusions and Iron Overload
Register FAQ Search Today's Posts Mark Forums Read

Transfusions and Iron Overload Blood and platelet transfusions, iron testing and treatments

Reply
 
Thread Tools Search this Thread
  #1  
Old Wed May 4, 2011, 03:26 AM
Neel Neel is offline
Member
 
Join Date: Dec 2010
Location: delhi india
Posts: 73
who can donate platelet

Hi ppl,

My father's Blood group is AB+. My bood group is A+. Can i donate platelet to him ? will there be any comlication ? At what frequency can i doante my platelets to him ? i mean how many times in a month and how often ?

regrds,

Neel
__________________
Father age 64 diagnosed with MDS RAEB-2, with 15%-18% blasts in October 2010. Only had blood and platelet transfusions. Ayurvedic treatment which showed result for arnd 5 months. Started Tahlidomide 100 mg started on 22 nd April 2011. Revolade 50 mg started on 2 nd april 2012.
Reply With Quote
  #2  
Old Wed May 4, 2011, 03:28 AM
Neel Neel is offline
Member
 
Join Date: Dec 2010
Location: delhi india
Posts: 73
Clarification

By complication i mean complication to my father, due to mismatch blood group ?

regrds,

Neel
__________________
Father age 64 diagnosed with MDS RAEB-2, with 15%-18% blasts in October 2010. Only had blood and platelet transfusions. Ayurvedic treatment which showed result for arnd 5 months. Started Tahlidomide 100 mg started on 22 nd April 2011. Revolade 50 mg started on 2 nd april 2012.
Reply With Quote
  #3  
Old Wed May 4, 2011, 12:06 PM
Neil Cuadra Neil Cuadra is offline
Owner
 
Join Date: Jul 2006
Location: Los Angeles, California
Posts: 2,553
Your father is lucky to be AB+ because that means he can receive transfusions of red blood from people with any blood type (A+, A-, B+, B-, AB+, AB-, O+, or O-).

For platelet transfusions, having a matched blood type is less important than for red blood cells, but in any case you can donate platelets for him.

How often you can donate is based on how long it takes your body to restore its platelet supply. This happens pretty fast so you can probably donate twice a month, maybe more often. The exact rules vary from country to country. You might check with the treatment center, or with a group like Rotary Blood Bank, to ask what the platelet donation rules are.
Reply With Quote
  #4  
Old Thu May 5, 2011, 12:24 AM
Neil Cuadra Neil Cuadra is offline
Owner
 
Join Date: Jul 2006
Location: Los Angeles, California
Posts: 2,553
Neel,

I forgot to mention that donation centers may let a relative donate more often than a stranger could. The usual rules about how often you can donate are based on ensuring maximum safety for the donor, so those rules may make people wait longer than is absolutely necessary.

When it's your own relative (like your father) getting your blood or platelets then in the United States they let you decide whether to donate more often as long as you are healthy enough to do so.
Reply With Quote
  #5  
Old Fri May 6, 2011, 12:02 AM
Neel Neel is offline
Member
 
Join Date: Dec 2010
Location: delhi india
Posts: 73
What Doctors Advice

Thanx niel,

The doctors here only advise AB+ blood and no other group. For platelets they suggest only the AB+ donor on cell seperator machine (SDP). In case of emergency and in absence of donor of AB+, they advise other blood group platelet on cell seperator machine (SDP). The platelet concentration from the same blood group AB+ is the last resort. Are they right ?

Is platelet refectoriness anything to do with what blood type platelet is being transfused ?

My father plaetelet increase from 10000 to 37000 after transfusion of 1 SDP unit (cell seperator machine) from same blood group AB+. Is the increase less ? Cos i find it increase in plaetlet count after transfusion on very much lesser side. The first transfusion in october 2010, with same blood group AB+ (SDP ) raised his platelet from 30000 to 80000.

regrds,

neel
__________________
Father age 64 diagnosed with MDS RAEB-2, with 15%-18% blasts in October 2010. Only had blood and platelet transfusions. Ayurvedic treatment which showed result for arnd 5 months. Started Tahlidomide 100 mg started on 22 nd April 2011. Revolade 50 mg started on 2 nd april 2012.
Reply With Quote
  #6  
Old Fri May 6, 2011, 04:55 PM
Neil Cuadra Neil Cuadra is offline
Owner
 
Join Date: Jul 2006
Location: Los Angeles, California
Posts: 2,553
Neel,

I would certainly follow the doctor's advice. There's a difference between which blood and platelets are compatible and which are most desirable, and that may explain it.

Platelet refractoriness means that platelet transfusions become less effective over time. This happens to some but not all patients. There are a couple of ways to reduce the risk of refractoriness. One is to use HLA-matched platelets. That's not the same as blood types, but the idea is the same: test the donor platelets for antigen matches with the patient. Another is to use single-donor platelets, meaning that the same donor keeps giving platelets to the same patient. That way the patient doesn't build up antibodies to the platelets of multiple donors.

If there are sufficient matched platelets for your father then there's no problem. But if they can't always get him the platelets he needs, make sure the doctors know that you are available to donate.
Reply With Quote
Reply


Thread Tools Search this Thread
Search this Thread:

Advanced Search

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

vB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Forum Jump

Similar Threads
Thread Thread Starter Forum Replies Last Post
Platelet Refractoriness clairekim AA 3 Tue Oct 6, 2015 09:18 PM
Role of mean platelet volume pdiitdelhi0204 Bone Marrow Failure 0 Sat Dec 21, 2013 08:15 AM
Platelet Apheresis Machine Neel Drugs and Drug Treatments 0 Wed May 9, 2012 03:14 AM
Stem cells could provide unlimited platelet supply tom30 Drugs and Drug Treatments 0 Wed Jan 12, 2011 07:31 AM
Platelet question Kathryn Transfusions and Iron Overload 2 Sun Dec 5, 2010 05:10 PM


All times are GMT -4. The time now is 04:08 AM.


Powered by vBulletin® Version 3.6.7
Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.
Forum sites may contain non-authoritative and unverified information.
Medical decisions should be made in consultation with qualified medical professionals.
Site contents exclusive of member posts Copyright © 2006-2020 Marrowforums.org