Home         Forums  

Go Back   Marrowforums > Bone Marrow Failure Diseases > MDS
Register FAQ Search Today's Posts Mark Forums Read

MDS Myelodysplastic syndromes

Reply
 
Thread Tools Search this Thread
  #1  
Old Wed Dec 4, 2019, 07:17 PM
maggiemag maggiemag is offline
Member
 
Join Date: Sep 2012
Location: Cincinnati, OH - United States
Posts: 92
Luspatercept

Hi everyone! You may already know this, but the drug Luspatercept has been FDA approved for treatment in beta thalassemia. Nope, not for low/intermediate risk MDS yet, but it’s approval for the one disease is very encouraging, I think. It has been shown to decrease transfusion dependence significantly in MDS. I think the target approval for MDS is April, 2020. So not that much longer to wait! It primarily was studied, I believe, for those MDS patients who have ring sideroblasts. I do not have those, so wonder if it will be strictly enforced. I asked my physician about that, and she thought there might be a way. We shall see! At any rate, we have some good news for a change.
__________________
Margaret, age 68, dx MDS 5 q- 5/09- now RCMD; also MGUS. TP53 and TET2 mutations

Last edited by Neil Cuadra : Wed Dec 4, 2019 at 07:40 PM. Reason: removed extraneous linebreak
Reply With Quote
  #2  
Old Wed Dec 11, 2019, 07:24 AM
Pearl Pearl is offline
Member
 
Join Date: Feb 2016
Location: New Jersey
Posts: 18
Quote:
Originally Posted by maggiemag View Post
Hi everyone! You may already know this, but the drug Luspatercept has been FDA approved for treatment in beta thalassemia. Nope, not for low/intermediate risk MDS yet, but it’s approval for the one disease is very encouraging, I think. It has been shown to decrease transfusion dependence significantly in MDS. I think the target approval for MDS is April, 2020. So not that much longer to wait! It primarily was studied, I believe, for those MDS patients who have ring sideroblasts. I do not have those, so wonder if it will be strictly enforced. I asked my physician about that, and she thought there might be a way. We shall see! At any rate, we have some good news for a change.
Your post started us looking and the first group of posts at the link below are reports about Luspatercept from the very recent ASH conference.

http://acceleronpharma.com/science-p.../luspatercept/
Reply With Quote
Reply


Thread Tools Search this Thread
Search this Thread:

Advanced Search

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

vB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Forum Jump

Similar Threads
Thread Thread Starter Forum Replies Last Post
MDS and Luspatercept clinical trial Leigh Clark MDS 0 Tue Sep 25, 2018 09:27 AM


All times are GMT -4. The time now is 07:18 PM.


Powered by vBulletin® Version 3.6.7
Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.
Forum sites may contain non-authoritative and unverified information.
Medical decisions should be made in consultation with qualified medical professionals.
Site contents exclusive of member posts Copyright © 2006-2020 Marrowforums.org