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Drugs and Drug Treatments ATG, Cyclosporine, Revlimid, Vidaza, Dacogen, ...

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  #1  
Old Wed May 1, 2013, 05:54 AM
Birgitta-A Birgitta-A is offline
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Location: Stockholm, Sweden
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Sapacitabine

Hi All,
Positive results for Sapacitabine for patients who failed Vidaza or Dacogen.
http://nz.finance.yahoo.com/news/cyc...110000300.html
Kind regards
Birgitta-A
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Old Wed May 1, 2013, 05:46 PM
Neil Cuadra Neil Cuadra is offline
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I'm curious why they limited their trial to patients ages 60 and up, and why the Phase 3 trial is limited to patients ages 70 and up. Are they considering sapacitabine for only that patient population?
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Old Thu May 2, 2013, 03:57 PM
Birgitta-A Birgitta-A is offline
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Sapacitabine

Hi Neil,
You know I usually only read abstracts - when an abstract is very interesting I get the article at the Hospital. Sapacitabine is still far away from me so I only know the facts in the abstract.
Kind regards
Birgitta-A
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Old Thu May 2, 2013, 08:40 PM
riccd2001 riccd2001 is offline
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Where I live there is a cut-off age limit of 65 for BMTs. So there is a need for further less invasive treatments for us older MDS patients who want to fight on for some extra time before our "expiration" date.
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Ric: Low-risk MDS (blasts <4%); 4 cycles Revlimid no positive response; PRBC transfusion dependent; so far, 392'units' over 8 3/4 years; BMB #4 (15/04/01) shows evolution to AML (blasts 20-30%) 47,XY,del(5) (q22q35),+21[24][cp24]/46,XY(1).
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