Home         Forums  

Go Back   Marrowforums > Bone Marrow Failure Diseases > Bone Marrow Failure
Register FAQ Search Today's Posts Mark Forums Read

Bone Marrow Failure Causes, treatment approaches, terminology, related diseases

Reply
 
Thread Tools Search this Thread
  #1  
Old Sat May 21, 2011, 12:17 PM
Birgitta-A Birgitta-A is offline
Member
 
Join Date: Oct 2007
Location: Stockholm, Sweden
Posts: 1,918
Thumbs up No AML from Neupogen or similar drugs

Hi All,
Here is a report about patients treated with Neupogen or similar drugs. The patients had no increased risk for AML transformation and a better overall survival. The results are in agreement with recent reports, confirming that GCSF treatment does not increase the risk of AML transformation.
http://www.abstractserver.com/mds201...k7nston62kni20

Kind regards
Birgitta-A
Reply With Quote
  #2  
Old Tue May 24, 2011, 10:02 PM
cheri cheri is offline
Member
 
Join Date: Nov 2010
Location: Tuckahoe New Jersey
Posts: 243
Neupogen vs Neulasta

Is there any indication/evidence that the results would be similar with Neulasta? My Dr seems to think that Neupogen is the safer alternative, and has heard some negative things about the longer lasting Neulasta...
Any more info out there we can look at--currently I take Neupogen 5 days post Vidaza...thanks!
__________________
Cheri Age 54; dx Oct 2009 AML, induction chemo only;dx MDS July 2010,- PRBC transfusion dependent; Results BMB 8/4/11--- 6-8% blasts; Danazol 100 mg 3xday; quit Exjade/ GI distress; platelets holding 40's; Fluctuation in blasts in blood--Neupogen 3-4xweek; off Revlimid again! Procrit weekly
Reply With Quote
  #3  
Old Wed May 25, 2011, 04:45 AM
Birgitta-A Birgitta-A is offline
Member
 
Join Date: Oct 2007
Location: Stockholm, Sweden
Posts: 1,918
Neupogen vs Neulasta

Hi Cheri,
As far as I remember I have not read anything about Neulasta but they never mention in the acstracts what type of granulocyte colony stimulating factor they use. We don't know if it is Neupogen, Neulasta or some other brand.
Kind regards
Birgitta-A
Neupogen 2 injections/week since neutropenic fever Sept 2007
Reply With Quote
  #4  
Old Wed May 25, 2011, 09:54 AM
cheri cheri is offline
Member
 
Join Date: Nov 2010
Location: Tuckahoe New Jersey
Posts: 243
Neupogen vs Neulasta

Hi Birgitta~
Well, the fact that you have been on regular Neupogen for 4 years speaks for itself.....
I wonder where we might find more information on Neulasta, and how it differs from several doses of Neupogen. My Dr says it's "long term" stimulator, but what does that mean, exactly...
__________________
Cheri Age 54; dx Oct 2009 AML, induction chemo only;dx MDS July 2010,- PRBC transfusion dependent; Results BMB 8/4/11--- 6-8% blasts; Danazol 100 mg 3xday; quit Exjade/ GI distress; platelets holding 40's; Fluctuation in blasts in blood--Neupogen 3-4xweek; off Revlimid again! Procrit weekly
Reply With Quote
  #5  
Old Wed May 25, 2011, 03:20 PM
Birgitta-A Birgitta-A is offline
Member
 
Join Date: Oct 2007
Location: Stockholm, Sweden
Posts: 1,918
Neupogen vs Neulasta

Hi cheri,
Amgen makes both drugs. Neulasta is a modern drug and stays longer in the body because it has a large chemical called polyethylene glycol (or PEG) added to one end of the Neupogen molecule. At the same time Neulasta is difficult to monitor - if you for example get pain from the joints the adverse effect will last much longer.
http://www.neulasta.com/patient/howc..._neupogen.html

When I have tried different drugs for iron overload like Ferriprox (not approved in the US) and a normal dose of Exjade I have been taking Neupogen every day to increase the very low WBCs. The same thing happened when I started to take Thalidomide 50 mg/day - I can only take 50 mg 4 times/week.
Kind regards
Birgitta-A
Reply With Quote
Reply


Thread Tools Search this Thread
Search this Thread:

Advanced Search

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

vB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Forum Jump

Similar Threads
Thread Thread Starter Forum Replies Last Post
Expanded Access to investigational Drugs for Treatment Use akita Insurance, Finances, Disability, Veterans Benefits 3 Wed Apr 27, 2011 01:30 PM
Neupogen Neel Drugs and Drug Treatments 5 Sun Apr 24, 2011 01:13 AM
Level for ANC Neel MDS 1 Sat Apr 9, 2011 04:59 AM
Updated warning for Aranesp and similar drugs Birgitta-A Drugs and Drug Treatments 5 Sun Jun 29, 2008 09:20 PM
News about Zolinza and similar drugs Birgitta-A Drugs and Drug Treatments 0 Sat Apr 12, 2008 06:20 AM


All times are GMT -4. The time now is 07:27 AM.


Powered by vBulletin® Version 3.6.7
Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.
Forum sites may contain non-authoritative and unverified information.
Medical decisions should be made in consultation with qualified medical professionals.
Site contents exclusive of member posts Copyright © 2006-2020 Marrowforums.org