FDA Approves Intravenous Vidaza for MDS

[Marrowforums]

Pharmion Corporation has received approval for intravenous (IV) administration of Vidaza (azacitidine) for the treatment of all subtypes of MDS. The U.S. Food and Drug Administration (FDA) formally notified the company of this approval on January 26, 2007. This expands the drug’s prior approval, which covered subcutaneous injection only. Vidaza can now be administered intravenously over a period of 10 to 40 minutes in a clinic, hospital, or physician’s office.

Intravenous Vidaza may give patients who were unable to tolerate subcutaneous injections an opportunity to try the drug. In earlier clinical trials, 35% of patients taking the drug subcutaneously had redness and inflammation of the skin at the injection site and 13% had other injection site reactions.

Pharmion Corporation has also received FDA approval of its application to test an oral form of Vidaza.

For further details, see Pharmion's news release.

[stevej]

Has anyone been on the Vidaza and can you tell me if it is working or not working? The medical release information seems supportive, but I really have not heard from anyone that is actually taking it.

[Neil Cuadra]

Originally Posted by stevej

Has anyone been on the Vidaza and can you tell me if it is working or not working? The medical release information seems supportive, but I really have not heard from anyone that is actually taking it.

There are a number of Marrowforums members taking Vidaza. One way to find them is to use the search page. Type "vidaza" in the Key Word(s) field and you'll find a number of threads where Vidaza is being discussed.