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MDS Myelodysplastic syndromes

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  #1  
Old Sat Apr 4, 2015, 10:32 PM
bailie bailie is offline
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MDS and CML?

I haven'y heard of this so this next week should be another learning situation. I have been diagnosed for the last 16 months for MDS. Now with the 9;22 chromosome the question will be "do I have CML?" or do I have both? I will be having my 11th BMB on Monday to get more information. Has anyone heard of someone having both MDS and CML?
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age 70, dx RAEB-2 on 11-26-2013 w/11% blasts. 8 cycles Vidaza 3w/Revlimid. SCT 8/15/2014, relapsed@Day+210 (AML). Now(SCT-Day+1005). Prepping w/ 10 days Dacogen for DLI on 6/9/2017.
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Old Sun Apr 5, 2015, 04:35 PM
DanL DanL is offline
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bailie,

i can't say that I've seen this one. there is mds unclassified, but it does not have the translocation that you have. when i talked to one of my doctors a couple of years ago, he indicated that the standard of practice was o treat the disease that most closely matched diagnosis and change over to the other disease's treatment if needed.

i do hope you get some clarity from the doctor this week
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MDS RCMD w/grade 2-3 fibrosis. Allo-MUD Feb 26, 2014. Relapsed August 2014. Free and clear of MDS since November 2014 after treatment with Vidaza and Rituxan. Experiencing autoimmune attack on CNS thought to be GVHD, some gut, skin and ocular cGVHD. Neuropathy over 80% of body.
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