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MDS Myelodysplastic syndromes

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Old Sat Apr 9, 2011, 02:16 AM
Neel Neel is offline
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Join Date: Dec 2010
Location: delhi india
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Level for ANC

Hi,

Wanted to know that at what level should the ANC be maintained. I mean someone with ANC below 500 should get the growth factors even if he is having no infection and no fever.

Neel
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Father age 64 diagnosed with MDS RAEB-2, with 15%-18% blasts in October 2010. Only had blood and platelet transfusions. Ayurvedic treatment which showed result for arnd 5 months. Started Tahlidomide 100 mg started on 22 nd April 2011. Revolade 50 mg started on 2 nd april 2012.
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Old Sat Apr 9, 2011, 04:59 AM
Birgitta-A Birgitta-A is offline
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Neupogen and similar drugs

Hi Neel,
The question of the level of neutrophils is under discussion. You can see many patients of this forum that manage with very low neutrophils like 0.1.
Other patients - like me - with dysfunctional white blood cells can get neutropenic fever as soon as the neutrophils are 0.5 or lower.

In Sweden the doctors don't think that Neupogen and similar drugs will cause AML so if the patient has got a severe infection they will give Neupogen. I have got 2 Neupogen injections/week since Sept 2007.
Kind regards
Birgitta-A
72 yo, dx MDS Interm-1 2006, transfusion dependent since dx, Thalidomide, Prednisone, Exjade and 2 Neupogen injections/week. No transfusions since Sept 2010. Latest counts HGB 12.7 platelets 112.
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