Home         Forums  

Go Back   Marrowforums > Bone Marrow Failure Diseases > AA
Register FAQ Search Today's Posts Mark Forums Read

AA Aplastic anemia

Reply
 
Thread Tools Search this Thread
  #1  
Old Tue Nov 10, 2015, 07:47 PM
Mimi45 Mimi45 is offline
Member
 
Join Date: Nov 2015
Location: Illinois
Posts: 1
Danazol to boost rbc?

I am currently classified as MAA. Due to low rbc count my doctor has suggested adding low dose Danazol to my current cyclosporine regimen. Despite decent hemoglobin level of 9.7, I'm still experiencing considerable fatigue and am easily winded upon comparatively minor exertion --- i.e. climbing a flight of stairs. Does anyone have experience to share about Danazol?
Reply With Quote
  #2  
Old Tue Nov 10, 2015, 08:25 PM
triumphe64 triumphe64 is offline
Member
 
Join Date: Feb 2008
Location: Dallas, Texas
Posts: 455
It worked for me. It took a few months to kick in.
__________________
Dallas, Texas - Age 81 - Pure Red Cell Aplasia began March 2005 - Tried IVIG - Then cyclosporine and prednisone. Then Danazol, was added. Then only Danazol . HG reached 16.3 March 2015. Taken off all meds. Facebook PRCA group https://www.facebook.com/groups/PureRedCellAplasia/
Reply With Quote
  #3  
Old Wed Nov 11, 2015, 05:37 PM
TASHMAC TASHMAC is offline
Member
 
Join Date: Oct 2012
Location: Cayman Islands
Posts: 56
My doctor also suggested danazol to boast my HGB, mine however was lower than yours and we were encountering hemolysis. It is worth a shot as I believe that if you have to chose between danazol and prednisone it is a "better" choice .... all relative though.

I tried it but it was not my friend as within 2 days of commencing I started having debilitating headaches/migraines and it made my cyclosporine toxic i.e. my trough levels went from about 200 to over 500 in about 48 hours. So I had to stop and unfortunately my hgb is still low as the hemolysis continues. It took me over 2 weeks to fully recover.

Good luck.
Reply With Quote
  #4  
Old Sat Nov 14, 2015, 01:39 AM
Robi1Knobi Robi1Knobi is offline
Member
 
Join Date: Mar 2007
Location: Austin, Texas USA
Posts: 98
I also have MAA

Hi there, Danazol did boost up my HGB, about an 11 now, after being on it since 2011. I did have to start Promacta this year due to platelets headed to low 20's. My WBC is still low. I hope this helps and that it works for you too!
__________________
Linda, 47 yo, married, mother of a teen, moderate AA w/ TERC mutation (2007 NIH), Pulmonary Fibrosis 2010, was on Danazol study (Aug 2011-2013 & restarted 9/14/15), last transfusion May 2011. On Promacta now. Needing a double lung and stem cell transplant.
Reply With Quote
Reply


Thread Tools Search this Thread
Search this Thread:

Advanced Search

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

vB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Forum Jump

Similar Threads
Thread Thread Starter Forum Replies Last Post
Danazol side effect pvinod AA 5 Sun Dec 18, 2022 03:42 PM
Danazol + cyclosporine teo Drugs and Drug Treatments 7 Fri Sep 18, 2015 02:34 PM
Danazol MDSPerth Drugs and Drug Treatments 1 Wed Sep 26, 2012 10:43 PM
Low ABS Retic, low normal RBC Tohobo Questions and Answers 10 Sun Feb 6, 2011 10:16 AM
e1905 Clinical Trial flowerlady Clinical Trials 84 Mon May 31, 2010 12:28 PM


All times are GMT -4. The time now is 08:35 AM.


Powered by vBulletin® Version 3.6.7
Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.
Forum sites may contain non-authoritative and unverified information.
Medical decisions should be made in consultation with qualified medical professionals.
Site contents exclusive of member posts Copyright © 2006-2020 Marrowforums.org