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#1
Fri Jul 15, 2011, 08:51 AM
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St Jude's BMT survival rate
St. Jude's improvement of survival rate for high risk leukemia patients.
http://www.sciencedaily.com/releases...0714120846.htm
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Marlene, wife to John DX w/SAA April 2002, Stable partial remission; Treated with High Dose Cytoxan, Johns Hopkins, June 2002. Final phlebotomy 11/2016. As of July 2021 HGB 12.0, WBC 4.70/ANC 3.85, Plts 110K. 
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#2
Fri Jul 15, 2011, 10:33 AM
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St Jude's BMT rates
Marlene,
Thanks for the article. I notice all the articles talk about improved BMT for leukemia but would it also apply to BMT for AA. Is there a difference in success for different types of disease? Thanks
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Jody, mother or Trevor 23. Diagnosed VSAA 3/11 , ATG cyclosporin 3/11 response 6/11, Relapse 1/13, Round 2 ATG 1/13
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#3
Fri Jul 15, 2011, 11:16 AM
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Hi Jody,
I don't really know the answer to that but it would make sense that it would work just as well in AA where ATG has failed and there is no matching donor for child. I think that's why it is so important to find out what you can from the different BMT centers on what protocols they use so you can make informed choice on where to go. You really want the least toxic, most effect protocol with good outcomes. Especially with GVHD. It saddens me to read about those who have successful BMTs but end up major GVHD.
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Marlene, wife to John DX w/SAA April 2002, Stable partial remission; Treated with High Dose Cytoxan, Johns Hopkins, June 2002. Final phlebotomy 11/2016. As of July 2021 HGB 12.0, WBC 4.70/ANC 3.85, Plts 110K.
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#4
Fri Jul 15, 2011, 02:57 PM
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Hi All!
Even though I'm and MDSer, I watched this AAMDS presentation (from March) on SCT for AA the other day and was very interested to learn about the differences in transplant for the two diseases. The presenter, Dr. Noel, said one key difference is that, in MDS, you typically want a little GVHD, to help kill off the cancerous stem cells in the marrow. In AA, you don't have those bad stem cells to worry about, so the aim is to, if possible, completely eliminate GVHD. So there's a bit more of a balancing act in the MDS cases. The whole lecture was really very fine; I recommend it. Take Care! Greg
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Greg, 59, dx MDS RCMD Int-1 03/10, 8+ & Dup1(q21q31). NIH Campath 11/2010. Non-responder. Tiny telomeres. TERT mutation. Danazol at NIH 12/11. TX independent 7/12. Pancreatitis 4/15. 15% blasts 4/16. DX RAEB-2. Beginning Vidaza to prep for MUD STC. Check out my blog at www.greghankins.com
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#5
Fri Jul 15, 2011, 03:37 PM
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Yeah, that makes sense. Same would hold true with AML/ALL.
__________________
Marlene, wife to John DX w/SAA April 2002, Stable partial remission; Treated with High Dose Cytoxan, Johns Hopkins, June 2002. Final phlebotomy 11/2016. As of July 2021 HGB 12.0, WBC 4.70/ANC 3.85, Plts 110K.
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