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MDS Myelodysplastic syndromes

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Old Tue Dec 14, 2010, 04:47 AM
Neel Neel is offline
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what does remission means

What does one mean by remission ? does remission means only the blood count being normal ? or does it means that disease/syndrome is no longer present ? How does one say that the patient is in remission ?
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Father age 64 diagnosed with MDS RAEB-2, with 15%-18% blasts in October 2010. Only had blood and platelet transfusions. Ayurvedic treatment which showed result for arnd 5 months. Started Tahlidomide 100 mg started on 22 nd April 2011. Revolade 50 mg started on 2 nd april 2012.
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Old Tue Dec 14, 2010, 01:09 PM
Neil Cuadra Neil Cuadra is offline
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Neel,

When you hear people speak of "remission" they usually mean the absence of the original symptoms (shortness of breath, bruising, etc.), normal blood counts, and normal results for other tests. For MDS that would include normal results from a bone marrow biopsy, i.e., no abnormal morphology (cell shapes) and no bad cytogenetics (chromosomes). But sometimes they mean that these goals have almost been achieved.

It's clearer when they say "partial remission" if symptoms or signs of disease have mostly disappeared, but some remain, and when they say "complete remission" if there are absolutely no signs of the disease.

Medical researchers are more precise about their terms. In a research paper they will normal define "remission" in terms of specific ranges of numbers for specific tests.
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