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AA Aplastic anemia

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Old Mon Nov 14, 2011, 02:22 PM
Ryan Jay Ryan Jay is offline
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Kidneys and colds

Hey everyone,

Quick question for you. I just fought off a cold last week, and I had some really wacky counts. My HGB was running at about 10.8 when it usually hovers around the low to mid 12s, and my WBCs were up around "6" when they usually settle in the mid 4s. Plts were steady as usual.

Anyway, I know this can happen during a cold, but can your kidneys also be affected? My creatinine shot up to the point where they decided to lower my cyclosporine a smidge. My kidneys also went kooky back in December too, when I had a really nasty cold....and then they seemed to settle down.

Any thoughts?
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Ryan Jay: 38-yo, dx SAA: 7/25/10, ATG: 8/10/10. CR with counts still rising. HGB: 13, Plt: 137 WBC 5.1 ANC
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Old Mon Nov 14, 2011, 05:09 PM
Robi1Knobi Robi1Knobi is offline
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elderberry

Hi Ryan,

Have you looked at the research on elderberry & its ability to fight colds/flu? I take it in the form of Juice Plus, but you can also buy elderberry jam, Sambucal (syrup you can get from a natural grocer), and elderberry wine (so I've heard!). Good luck & hope you stay healthy from now on ). Linda
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Linda, 45 yo, married, mother of a 13 yr old, moderate AA with TERC mutation (2007 NIH), now moderate AA (Nov 2009), Pulmonary Fibrosis 2010, not a transplant or immune suppressant candidate, was on Danazol study (Aug 2011-2013), last transfusion May 2011, trying to learn about nutritional help.
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Old Tue Nov 15, 2011, 08:41 AM
Marlene Marlene is offline
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Were you drinking enough fluids? You really have to up the intake of fluids when you have a cold.

I'm a fan of elderberry also. That, coupled with vitamin c and zinc can go a long way to shortening a cold.
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Marlene, wife to John DX w/SAA April 2002, Stable partial remission; Treated with High Dose Cytoxan, Johns Hopkins, June 2002. FE is down to 384.
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Old Wed Nov 16, 2011, 12:49 PM
Lbrown Lbrown is offline
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Yes. Clearing dead pathogens puts a strain on the kidneys. This happens to me. I am currently only on exjade (ie no cyclo or tacro or anything else that might affect the kidneys).

One week my creatinine went up to 186 when I felt I was fighting something, then 2 weeks later it was back to 93. Mine always seems to go up when I feel like I am fighting a cold.

Drinking more water might help, of course I never remember either.

Deb
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Old Sun Jan 1, 2012, 05:40 AM
suz suz is offline
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Agree with Marlene

I have AA and PNH and had food poisoning 2 years ago, taking my GFR down to 15. Was lucky to avoid dialysis. Had massive hemolysis from the infection and fever. Anyway was given IV fluids plus drank as much liquid as possible inpatient for 8 days. GFR and creatinine gradually rose to nearly normal.

I get a renal panel every 2 weeks. I definitely notice if I'm not drinking enough fluids ( coffee doesn't count:-)) my GFR falls, sometimes to 46. Creatinine goes up a bit, not bad.

Kidney issues are my main cercern if and when I do ATG/cyclo. I just hope I'm not kicked off of treatment mid way from kidney damage. I did read somewhere about meds that can be taken to help prevent damage, eg, worsing Chronic Kidney Disease. Will be researching cyclo and kidney issues before treatment. Counts still not too bad for now.
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AA/PNH Dx 1998, Prednisone 2001 to 2009 very slow tapper, started Warfarin 2001, Soliris 2011, slowly falling Neutrophils
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Old Sun Jan 1, 2012, 05:45 AM
suz suz is offline
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Infection

To my knowledge my kidney function only went down with a fever (100.9) and chest infection recently due to PNH hemolysis, a strain on the kidneys.
So I think it's fluid intake, not the infection itself. May be other reasons I'm not aware of since I haven't done cyclo yet and don't know all the ins and outs of it.
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AA/PNH Dx 1998, Prednisone 2001 to 2009 very slow tapper, started Warfarin 2001, Soliris 2011, slowly falling Neutrophils
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